张红雨,教授,博士生导师 |
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学 历 |
1988.09-1992.07 山东大学生物系
理学学士 1992.08-1997.01 中国科学院生物物理研究所 理学博士 |
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职 历 |
1997.02-1998.10 山东师范大学生命科学学院
讲师 1998.11-2000.06 山东师范大学生命科学学院
教授 2000.07-2009.01 山东理工大学生命科学学院
教授、博导 2009.02至今 华中农业大学生命科学技术学院 教授、博导 (2010.09-2010.10
新加坡南洋理工大学生命科学学院
客座教授) |
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研究方向 |
系统进化生物学(生命起源进化机制) 系统化学生物学(进化启发的药物发现) |
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主要兼职 |
中国空间科学学会空间生命起源与进化专业委员会副主任委员 Current Computer-Aided Drug Design(SCI收录)编委 Neural Regeneration
Research(SCI收录)编委 Genomics Insights编委 Research in Pharmaceutical
Biotechnology编委 Open Journal of Genomics编委 |
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电 话 |
027-87280877 |
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电子邮件 |
zhy630@mail.hzau.edu.cn |
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工作单位 |
华中农业大学生命科学技术学院/作物遗传改良国家重点实验室/生物信息中心 |
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研究成果 |
代表性论文: l Sheng P., Xu J.,
Saccone G., Li K.B., Zhang H.-Y.*,
Discovery and characterization of endo-xylanase and β-xylosidase from a
highly xylanolytic bacterium in the hindgut of Holotrichia parallela larvae. J Mol Catal B-Enzym. 2014, 105, 33-40
(SCI, IF2.823) l Zhang B., Zheng
W.W., Zhao W.J., Xu X.N., Liu J. & Zhang
H.-Y. *. Intraguild predation among the predatory mites Amblyseius
eharai, Amblyseius cucumeris and Amblyseius barkeri, Biocontrol Science and Technology, 2013, 24: 1, 103-115, DOI:
10.1080/09583157. 2013.849658 l Jiang Y.-Y., Kong D.-X., Qin T., Li X., Caetano-Anollés G., Zhang H.-Y. (2012) The impact of oxygen on metabolic
evolution: a chemoinformatic investigation. PLoS Comput. Biol. 8: in press. (corresponding author) l Kim K. M., Qin T., Jiang Y.-Y., Chen L.-L., Xiong M., Caetano-Anollés D., Zhang H.-Y., Caetano-Anollés G. (2012)
Protein domain structure uncovers the origin of
aerobic metabolism and the rise of planetary oxygen. Structure
20: 67-76. (co-corresponding author) (Preview:
Saito, M. A.
Structure 2012, 20: 1-2) (Featured by Science: http://news.sciencemag.org/sciencenow/2012/01/the-first-oxygen-users.html) l Wang Z.-Y., Fu L.-Y., Zhang H.-Y. (2012) Can medical genetics and evolutionary biology inspire drug target
identification?
Trends Mol. Med.
18: 69-71. (corresponding author) (Featured article) l Zhu Q., Qin T., Jiang Y.-Y., Ji C., Kong D.-X., Ma B.-G., Zhang H.-Y. (2011) Chemical basis of
metabolic network organization. PLoS Comput. Biol. 7: e1002214. (corresponding author) l Wang M., Jiang Y.-Y., Kim K. M., Qu G., Ji H.-F., Mittenthal J. E., Zhang H.-Y., Caetano-Anollés G. (2011) A universal molecular clock of protein folds and
its power in tracing the early history of aerobic metabolism and planet
oxygenation. Mol.
Biol. Evol. 28:
567-582. (co-corresponding author) l Zhang H.-Y., Chen L.-L., Li,
X.-J., Zhang J. (2010) Evolutionary inspirations for drug
discovery. Trends Pharmacol. Sci. 31: 443-448. (corresponding author) l Ji H.-F., Chen L., Jiang Y.-Y., Zhang H.-Y. (2009) Evolutionary formation of new protein folds
is linked to metallic cofactor recruitment. BioEssays 31: 975-980. (corresponding author) l Ji H.-F., Kong D.-X., Shen L.,
Chen L.-L., Ma B.-G., Zhang H.-Y. (2007) Distribution
patterns of small-molecule ligands in the protein universe and implications
for origin of life and drug discovery. Genome Biol. 8: R176. (corresponding
author) l Zhang H.-Y., Sun
Y.-M., Wang X.-L. (2003) Substituent
effects on O-H bond dissociation enthalpies and ionization potentials of
catechols: a DFT study and its implications in rational design of phenolic
antioxidants and elucidation of structure-activity relationships for
flavonoid antioxidants. Chem. Eur. J. 9: 502-508. (corresponding author) l Zhang H.-Y., Sun Y.-M.,
Wang X.-L. (2002) Electronic
effects on O-H proton dissociation energies of phenolic cation radicals. A
DFT study. J. Org. Chem. 67:
2709-2712. (corresponding author) |
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备 注 |
2011年获得教育部自然科学二等奖(首位)。 2005年获得中国化学会青年化学奖。 1999年获得第三届中国药理学会Servier奖。 |
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