张京芬，女，研究员，美国密苏里大学计算机系数字化生物实验室。1993年7月，华中师范大学理论数学专业学士。1998年获得计算机科学专业硕士，导师为黄文奇，论文题目为《求解等圆和不等圆packing问题的快速近似算法》。2006年7月获得中国科学院计算技术研究所计算机科学专业博士，导师为高文，博士论文为《串联质谱数据预处理》。

工作经历

2006年12月至今，美国密苏里大学计算机系数字化生物实验室，研究员

2001年9月-2006年6月，中科院计算技术研究所，联合实验室，研究助理

1998年7月-2001年9月，广州金鹏集团公司，研发中心，软件工程师

1995年9月-1998年7月华中科技大学，计算机系，研究助理

开发软件

研究资助基金

NIH R01 GM100701-01, Development of MUFOLD for Building High-Accuracy Protein Structure Models。（项目共同负责人）

已发表文章：

期刊文章

  1. N. Ahsan, K.N. Swatek, J. Zhang, J.A. Miernyk, D. Xu, J.J. Thelen, "Scanning mutagenesis" of the amino acid sequences flanking phosphorylation site 1 of the mitochondrial pyruvate dehydrogenase complex, Front Plant Sci., 2012; 3:153.
  2. Z. Yuan, C. Liu, H. Wang, R. Sun, Y. Fu, J. Zhang, L. Wang, H. Chi, Y. Li, L. Xiu, W. Wang and S. He, "pParse: a method for accurate determination of monoisotopic peaks in high-resolution mass spectra", Proteomics. 2012;12(2):226-35.
  3. Z. He, J. Zhang, Y. Xu, Y. Shang and D. Xu, "Protein structural model selection based on protein-dependent scoring function", Statistics and Its Interface, 2012;5: 109-115.
  4. Zhang J, Wang Q, Vantasin K, Zhang J, He Z, Kosztin I, Shang Y, Xu D. "A multi-layer evaluation approach for protein structure prediction and model quality assessment", Proteins: Struct Funct Bioinformatics, 2011;79(10):172-84.
  5. X. Shi, J. Zhang*, Z. He, Y. Shang, and D. Xu, "A sampling-based method for ranking protein structural models by integrating multiple scores and features", Current Protein and Peptide Science, 2011; 12(6):540-8. *denotes co-first authors.
  6. J. Zhang, Q.G. Wang, B. Barz, Z.Q. He, I. Kosztin, Y. Shang, and D. Xu, "MUFOLD: A New Solution for Protein 3D Structure Prediction", Proteins: Struct Funct Bioinformatics, 2009; 78(5), 1137-52.
  7. J. Zhang, D. Xu, W. Gao, G. Lin, S. He, "Isotope Pattern Vector Based MS/MS Data Calibration for Improved Peptide and Protein Identification", Rapid Commun Mass Spectrom., 2009; 23, 3448–3456.
  8. J. Zhang*, S.M. He, C.X. Ling, X .J. Cao, R. Zeng, and W. Gao, "PeakSelect: preprocessing tandem mass spectra for better peptide identification", Rapid Commun Mass Spectrom., 2008; 22(8), 1203-1212. *denotes co-corresponding authors.
  9. S. Sun, C. Yu, Y. Qiao, Y. Lin, G. Dong, C. Liu, J. Zhang, Z. Zhang, J. Cai, H. Zhang and D. Bu, "Deriving the probabilities of water loss and ammonia loss for amino acids from tandem mass spectra", J. Proteome Res., 2008; 7 (01), 202–208.
  10. L. Wang, D. Li, Y. Fu, H. Wang, J. Zhang, Z. Yuan, R. Sun, R. Zeng, S. He, and W. Gao, "pFind 2.0: a software package for peptide and protein identification via tandem mass spectrometry". Rapid Communications in Mass Spectrometry, 2007; 21, 2985-2991.
  11. C. Yu, Y. Lin, S. Sun, J. Cai, J. Zhang, Z. Zhang, R. Chen, and D. Bu, "An iterative algorithm to quantify the factors influencing peptide fragmentation for ms/ms spectrum", J Bioinform Comput Biol., 2007; 5 (2),297-311.
  12. R. Sun, Y. Fu, D. Li, J. Zhang, X. Wang, Q. Sheng, R.Zeng, Y. Chen, S. He, and W. Gao, "Computational Proteomics Based on Spectrometry Technology", Science in China Ser. E Information Sciences, 2006; 36, 222-234.
  13. J. Yu, J. Wang, W. Lin, …, J. Zhang, …, H. Yang, "The Genomes of Oryza sativa: A History of Duplications", PLoS Biol. 2005; 3(2), e38, 0266-0281. *denotes the 56th of 117 authors.
  14. J. Zhang, W. Gao, J.J. Cai, S.M. He, R. Zeng, and R.S. Chen, "Predicting Molecular Formulas of Fragment Ions with Isotope Patterns in Tandem Mass Spectra", IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2005; 2(3), 217-230.
  15. J. Zhang, S.M. He, J.J. Cai, X.J. Cao, R.X. Sun, Y. Fu, R. Zeng and W. Gao, "Preprocessing of tandem mass spectrometric data based on decision tree classification", Genomics, Proteomics & Bioinformatics, 2005; 3(4), 231-237. *denotes corresponding author.
  16. H.C. Lu, Y. Zhao, J. Zhang, Y.L. Wang, W. Li, X.P. Zhu, S. W. Sun, J.Y. Xu, L.J. Ling, L. Cai, D.B Bu, and R.S. Chen, "Date of origin of the SARS coronavirus strains", BMC Infectious Diseases, 2004;4:3.
  17. H.C. Lu, X.P. Zhu, H.F. Li, G. Skogerbo, J. Zhang, Y. Zhang, L. Cai, Y. Zhao, S.W. Sun, J.Y. Xu, D.B. Bu, and R.S. Chen. "The interactome as a tree-an attempt to visualize the protein–protein interaction network in yeast", Nucleic Acids Res. 2004; 32(16), 4804-4811.
  18. Z. Qi, Y. Hu, W. Li, Y.J. Chen, Z.H. Zhang, S.W. Sun, H.C. Lu, J. Zhang, D.B. Bu, L.J. Ling & R.S. Chen, "Phylogeny of SARS-CoV as inferred from complete genome comparison", Chinese Science Bulletin, 2003;48(12),1175-1178.
  19. D. Bu, Y. Zhao, L. Cai, H. Xue, X. Zhu, H. Lu, J. Zhang, S. Sun, L. Ling, N. Zhang, G. Li and R. Chen, "Topological structure analysis of the protein-protein interaction network in budding yeast", Nucleic Acids Research, 2003; 31(9), 2443-2450.
  20. W. Huang, R. Xu, W. Chen, and J. Zhang, "Physicalification and personification for solving unequal circle packing and CNF-SAT problems", Journal of Huazhong University of Science and Technology, 1998; 26(9), 5-7.
  21. J. Zhang, "The Moore-Penrose inverse about product and sum of morphism", Journal of Central China Normal University, 1993; 27(3), 294-297. *denotes corresponding author.

会议文章

  1. J. Zhang and D. Xu, "Fast Algorithm for Clustering a Large Number of Protein Structural Decoys", Proceedings of the 2011 IEEE International Conference on Bioinformatics and Biomedicine (BIBM '11), 2011: 30-36.
  2. C.G. Yu, Y. Lin, S.W. Sun, J.J. Cai, J. Zhang, Z. Zhang, R.S. Chen, D.B. Bu, "An iterative algorithm to quantify the factors influencing peptide fragmentation for ms/ms spectrum", Computational systems bioinformatics, Stanford, USA, 2006:353-60.
  3. J. Zhang, D.B. Bu, J.Y. Xu, S.M. He, W. Gao, and M. Li, "LSA: More Accurate DNA Fragment Assembly", Proceedings of the RECOMB 2003 satellite meeting on DNA Sequencing Technologies and Computation, Stanford, USA, May, 2003.
  4. J. Zhang, W. Gao, J. J. Cai, S.M. He, R. Zeng, and R.S. Chen, "Predicting Molecular Formulas of Fragment Ions with Isotope Patterns in Tandem Mass Spectra", Human Proteome Organisation 3rd Annual World Congress, Beijing, China, Oct., 2004.
  5. J. Zhang, S.M. He, J.J. Cai, X.J. Cao, R.X. Sun, Y. Fu, R. Zeng and W. Gao, "Preprocessing of tandem mass spectrometric data based on decision tree classification", China National Computer Conference, Wuhan, China, Oct., 2005.

参与撰写的图书

发明专利

软件著作权

联系方式：

E-mail：zhangjingf@missouri.edu

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